The Liverpool legend has backed the 22-year-old to come in for Liverpool captain Jordan Henderson.
Winks has played only once for England, against Lithuania in October 2017, but won praise for his performance and has previously excelled against Real Madrid in particular, but also Barcelona in the Champions League.
In fact, before he turned out in the 1-0 victory in the Vilniaus FF Stadium, Winks had been mooted for a potential Spanish call up, by virtue of his Spanish grandparents making him potentially eligible for 'La roja'.
The youngster however chose the 'Three Lions' and Carragher thinks that Winks should start against the world-class Spanish midfield, telling 'Sky Sports':
"In midfield, maybe Harry Winks. He played really well for Spurs against Barcelona in the Champions League, against similar type of players. Again, it won't be easy, but I think in Seville on Monday night, we are going to have to do as well as we can to keep the ball against Spain. Winks is as good as anyone who can come in for Jordan Henderson in terms of technical ability."
England's midfield, and the lack of creativity in it, is what many view as the team's main deficiency in competing with the best teams in the world, against whom they have repeatedly come unstuck.
"England have real problems coming up against the top sides," Carragher said. "I don't know how long it is since we beat them. Looking back at the World Cup, yes it was a fantastic summer, but as soon as we came up against a top side who were on our level or slightly above us in Croatia we lost. Before that, we always played teams we would fancy ourselves against really.
"It is difficult, but this game [against Spain] is as much about performance as it is about result."