The Barca boss is well aware that his side are just three wins away from lifting the Copa del Rey and as such, he is not prepared to take chances by resting players.
The former Athletic Bilbao manager has been pondering which team to put out against Marcelino Garcia Toral's side on Thursday and after almost seeing his side surrender their unbeaten run in La Liga at the weekend against Alaves, Valverde is prepared to play his best side against 'Los Che'.
Barca are expected to field regular cup goalkeeper Jasper Cillessen in goal, with Sergi Roberto, Gerard Pique, Samuel Umtiti and Jordi Alba lining up in front of him. Brazilian midfielder Paulinho could come in for compatriot Philippe Coutinho to add solidity to the midfield, with the rest of the lineup made up of Ivan Rakitic, Sergio Busquets, Andres Iniesta, Lionel Messi and Luis Suarez.
Meanwhile, Valencia have been hit by a major blow with the news that Gonçalo Guedes will miss out due to a muscle injury.