The Croatian striker was given his first start of the season by Max Allegri as he continued his recuperation from a World Cup campaign that ended in final defeat, and he repaid him in kind.
A ball from Joao Cancelo was tipped by Strakosha in goal, deflecting into the path of Cristiano Ronaldo.
The Portuguese winger must have thought that the time for his first Serie A goal had finally come, two yards out from an open net. Unfortunately for Ronaldo, he succeeded only in kicking the ball onto the back of his leading leg with the deflection from the goalkeeper putting it just behind his stride.
All was not lost however, as the ball flicked up nicely for Mandzukic to smash a volley home and set Juve on their way to a probably victory.
Ronaldo was able to see the funny side, smiling as he and Mandzukic celebrated with the team mates.