Pep Guardiola's side are currently unbeaten in their opening 16 games in all competitions and are five points clear at the top of the Premier League table. City have won 14 consecutive games, a new club record, and have already scored 49 goals this term.
Arsenal are also in fine form, having lost just one in their last 13 games in all competitions but they remain nine points behind their opponents on Sunday.
City have no new injury concerns, with Vincent Kompany remaining on the sidelines and Benjamin Mendy a long-term absentee.
Wenger will be hoping Sead Kolasinac recovers from a hip injury in time for the game on Sunday while Shkodran Mustafi, Santi Cazorla, Calum Chambers, Danny Welbeck, David Ospina are all still sidelined.
Potential lineups:
Man City: Ederson; Walker, Stones, Otamendi, Delph; Fernandinho, Gundogan, De Bruyne; Sane, Sterling, Aguero.
Arsenal: Cech; Koscielny, Mertesacker, Monreal; Bellerin, Ramsey, Xhaka, Kolasinac; Ozil, Sanchez, Lacazette.