The return of Europe's premier club competition following the international break brings the biggest clubs back together, including a big clash between the Catalans and the club from Lombardy.
Guillermo Amor, the director of institutional relations at Barcelona, has singled out Mauro Icardi as the player his side need to watch out for at the Camp Nou.
"He's a very good player. With Icardi, all we can expect, the night is going to be difficult," he told 'Gazzetta dello Sport'.
Argentine, Icardi came through 'La Masia' as a youngster - Barcelona's academy - before deciding to leave the city and move to Italy, where he has since made a name for himself.
"It's true that our youth players can succeed away from Camp Nou," Amor added. "Last season, Inter also had Rafinha playing well."
Finally, he called for calm after a recent run of bad results for Barcelona: "We've played games where we were not so good, and some which went against the team. Then there was the game at Valencia where we could have won, but it ended in a draw."