The 42 entrants to this season's competition have been split into four seeding pots, with one side from each pot to make up each of the 12 groups.
The pot seedings have been based on the club coefficients from the last five years.
As in the Champions League, clubs from the same country cannot play each other at this stage, whilst teams from Russia and Ukraine may also not be drawn together.
Whatsmore, for countries with two or more representatives, clubs have been paired together to ensure that the games involving those teams are split across the two different kick-off times (18:55 CET and 21:00 CET).
The pairings are:
Sevilla & Real Betis
Arsenal & Chelsea
Zenit & Spartak Moskva
Dynamo Kyiv & Vorskla
Beşiktaş & Fenerbahçe
Salzburg & Rapid Wien
Olympiacos & PAOK
Anderlecht & Standard Liège
Lazio & AC Milan
Marseille & Bordeaux
Celtic & Rangers
RB Leipzig & Eintracht Frankfurt
Apollon Limassol & AEK Larnaca
Rosenborg & Sarpsborg
Slavia Praha & Jablonec
Again, the pairing system works the same as it did for the Champions League draw, so if one of the paired sides is drawn in group A, B, C, D, E or F, the other will automatically be placed in group G, H, I, J, K or L.
The pots for the draw are as follows:
Pot 1
Sevilla (ESP) 113.000
Arsenal (ENG) 93.000
Chelsea (ENG) 82.000
Zenit (RUS) 78.000
Bayer Leverkusen (GER) 66.000
Dynamo Kyiv (UKR) 62.000
Beşiktaş (TUR) 57.000
Salzburg (AUT) 55.500
Olympiacos (GRE) 54.000
Villarreal (ESP) 52.000
Anderlecht (BEL) 48.000
Lazio (ITA) 41.000
Pot 2
Sporting CP (POR) 40.000
Ludogorets (BUL) 37.000
København (DEN) 34.000
Marseille (FRA) 32.000
Celtic (SCO) 31.000
PAOK (GRE) 29.500
AC Milan (ITA) 28.000
Genk (BEL) 27.000
Fenerbahçe (TUR) 23.500
Krasnodar (RUS) 23.500
Astana (KAZ) 21.750
Rapid Wien (AUT) 21.500
Pot 3
Real Betis (ESP) 21.399
BATE Borisov (BLR) 20.500
Qarabağ (AZE) 20.500
Dinamo Zagreb (CRO) 17.500
RB Leipzig (GER) 17.000
Eintracht Frankfurt (GER) 14.285
Malmö (SWE) 14.000
Spartak Moskva (RUS) 13.500
Standard Liège (BEL) 12.500
Zürich (SUI) 12.000
Bordeaux (FRA) 11.283
Rennes (FRA) 11.283
Pot 4
Apollon (CYP) 10.000
Rosenborg (NOR) 9.000
Vorskla Poltava (UKR) 8.226
Slavia Praha (CZE) 7.500
Akhisar Belediyespor (TUR) 7.160
Jablonec (CZE) 6.035
AEK Larnaca (CYP) 4.310
Vidi (HUN) 4.250
Rangers (SCO) 3.725
Dudelange (LUX) 3.500
Spartak Trnava (SVK) 3.500
Sarpsborg (NOR) 3.485