With just a year remaining on his contract in London, Dembele could be sold this summer with replacements already allegedly being lined up.
The Chinese Super League (CSL) had been tipped as a likely destination but it seems plenty of Italian clubs are also interested.
The aforementioned media outlet suggests Juventus, Napoli and Inter would be keen on bringing Dembele to the Serie A, especially given his talents in midfield.
Current manager Mauricio Pochettino has previously described the Belgium international as a "genius" and he has no doubt played a key part in Spurs rise to the elite of European football.
However, both parties reportedly feel a change is in order but a potential move may have to wait until Belgium's participation in this summer's World Cup is over.