The former Bolton defender has been a more regular feature in the Arsenal team since Unai Emery's arrival, and he will likely start one of the team's most crucial games of the season.
A win will take them above their fierce rivals in the table, but Holding thinks that the confidence boost from such a result will be almost as worthy as the points at stake.
"We want to beat Tottenham and give fans the bragging rights and let them enjoy their weekend." the 23-year-old centre-back told the 'Daily Mail'.
"It should be a good game. Obviously we're on a good run. They've picked up a bit now. It all comes down to that we want to win it for the fans.
"Our fans will be behind us and we've just got to prove to them that we can beat Tottenham. I wouldn't expect anything less."