Karl Toko Ekambi, Bruno Guimaraes and Moussa Dembele scored for Lyon as they made it 16 points from their last six matches to sit two points behind leaders Paris Saint-Germain.

Lille can leapfrog them if they win at Saint-Etienne on Sunday evening. Reims, who had Moreto Cassama sent off after 33 minutes, remain fourth from bottom and look destined for a relegation dog fight.

Toko Ekambi, returning from suspension, proved the key for Lyon, hitting the post early on before scoring the opener in the 22nd minute with a header at the back post from a cross by Memphis Depay. He also created the second -- Guimaraes's first for Lyon -- four minutes after the break, the Brazilian's shot taking a deflection off Marshall Munetsi.

Toko Ekambi also teed up Dembele for the third shortly after he came on as a substitute for Tino Kadewere who had hit the post in the first half and had a goal ruled out for offside. Cassama was sent off for a foul on Depay when he looked to be in on goal.