Matches Quarter-finals - MLS Next Pro 2022

End

Quarter-finals

Columbus Crew II

4-1

Rochester New York

24 SEP 2022

End

Quarter-finals

Toronto II

1-0

Philadelphia Union II

25 SEP 2022

End

Quarter-finals

St. Louis II

2-0

North Texas

26 SEP 2022

End

Quarter-finals

Tacoma Defiance

2 (5-4) 2

Houston Dynamo II

26 SEP 2022