Pep Guardiola has made three changes from the first leg, most noteably including Thomas Muller, who he surprisingly left out last time round.
The German replaces Thiago Alcantara, and is expected to line-up attackingly alongside Lewandowski.
Jerome Boateng comes in for Bernat in defence, and finally Franck Ribery is selected over Kingsley Coman on the wing.
Diego Simeone makes only one change to the team which he fielded at the Calderon last week.
Diego Godin who missed the last game through injury comes in to replace Stefan Savic in the Atletico defence.
Bayern Munich XI (4-3-3): Neuer, Boateng, Lahm, Alaba, Vidal, Alonso, Costa, Martinez, Muller, Lewandowski, Ribery
Subs: Ulreich, Tasci, Thiago, Rafinha, Gotze, Coman, Kimmich
Atletico Madrid XI (4-4-2):Oblak, Juanfran, Godin, Gimenez, Luis, Gabi, Augusto, Koke, Saul, Griezmann, Torres
Subs: Moya, Savic, Lucas, Thomas, Carrasco, Correa, Vietto