Jindrich Tripisovsky's side were up against a side in the bottom half of the table- 3rd bottom. The visitors went ahead in the 30th minute through Michal Skoda.
Slavia Prague didn't level until the 2nd half when Tomas Soucek scored in the 63rd minute. He scored their 3rd 10 minutes later. Between both goals, Marek Kodr put the hosts 2-1 up at the Sinobo Stadium.
Slavia Prague have won 11 and drew 2 so far in the league, with 13 games played. They are top followed by Viktoria Plzen.
After the league match, they now face a tough week that sees them play Barcelona in the Champions League.