Sevilla: Sergio Escudero, Ever Banega and Sergio Rico will be available, despite minor injury concerns, but Jesus Navas is sidelined. Simon Kjaeu and Sebastein Corchia are also in contention after returning to training this week.
Real Madrid: Cristiano Ronaldo is ruled out of the game after sustaining an ankle injury against Barcelona on Sunday. Isco and Dani Carvajal will also play no part for 'Los Blancos'.
Sevilla interim boss Joaquin Caparros:
"I would like the C or D team to come. They have a starting XI made up of world-class players, the best. The rest of their players are internationals.
"It's going to be a very difficult game. Some of them who usually play will play, for sure."
Real Madrid manager Zinedine Zidane:
"We have three La Liga games to go and tomorrow we will give our all. We hope to end up as high up the table as possible.
"It is a chance to get three points, but we know that they want to play their game. You are about to see a special match and that is the important factor."
Did you know?
Real Madrid thrashed Sevilla 5-0 in the first fixture at the Bernabeu. Cristiano Ronaldo scored a double whilst Nacho, Toni Kroos and Achraf Hakimi netted the other three.
Form:
Possible lineups:
Sevilla: Soria; Layun, Mercado, Lenglet, Escudero, N’Zonzi, Banega, Sarabia, Correa, Nolito, Ben Yedder.
Real Madrid: Navas; Nacho, Varane, Ramos, Marcelo, Modric, Casemiro, Kroos, Bale, Benzema, Asensio.