Arsenal:
Arsene Wenger looks set to continue his rotation policy for the visit of Red Star. Jack Wilshere, Theo Walcott and Olivier Giroud are expected to come in, while Mesut Ozil, Alexandre Lacazette and Alexis Sanchez won't feature at all.
Shkodran Mustafi (hamstring), Sead Kolasinac (hip), Santi Cazorla (ankle), Danny Welbeck and David Ospina (both groin) will all watch from the sidelines.
Red Star Belgrade:
The visitors will be without left-back Milan Rodic, who misses out after picking up a red card in the reverse fixture a fortnight ago.
Recent form:
Possible lineups:
Arsenal: Cech; Debuchy, Elneny, Holding; Nelson, Coquelin, Willock, Maitland-Niles; Walcott, Wilshere; Giroud
Red Star Belgrade: Borjan; Stojkovic, Savic, Le Tallec, Babic; Srnic, Kanga, Donald, Krsticic, Radonjic; Boakye