Bayern Munich are facing the possibility of not being able to field a team for Friday's Bundesliga encounter with Borussia Moenchengladbach after Leroy Sane and Dayot Upamecano joined the long list of players hit by Covid-19 on Tuesday.
"Both players are well and are self-isolating," Bayern said in a statement.
The two were tested on Monday with young defender Josip Stanisic who tested negative and was permitted to join group training.
It takes to eight the number of Bayern players who have now been sidelined by Covid.
Manuel Neuer, Kingsley Coman, Corentin Tolisso, Omar Richards, Lucas Hernandez and Tanguy Nianzou have already tested positive for the coronavirus after returning from their vacation.
In December, the Bavarians said they would be without Germany midfielder Joshua Kimmich for up to four weeks after he contracted the virus.