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Fabio Cannavaro suffered heartache at the hands of former employers Tianjin Quanjian, who end Guangzhou Evergrande's Champions League bid.
Buriram United, Zob Ahan and Al Duhail all took the advantage in their attempts to reach the AFC Champions League quarter-finals.
Guangzhou Evergrande nullified the twin threat of Alexandre Pato and Anthony Modeste to earn a 0-0 draw at Chinese rivals Tianjin Quanjian in the Asian Champions League last 16 on Tuesday.
There were wins for Kashima Antlers and Jeju United in the AFC Champions League while Shanghai Shenhua and Sydney FC shared the spoils.
Fabio Cannavaro's return to Guangzhou Evergrande as head coach got off to a frustrating start on Wednesday when his team was held to a 1-1 draw by Thailand's Buriram United in the opening round of the AFC Champions League.