Barcelona were given a glimpse of hope against Real Betis, as Lionel Messi expertly converted a penalty Jordi Alba had won, before Lo Celso got one back for Betis.
Few would have backed Real Betis to cause an upset at Camp Nou on Sunday given their irregular league form of late, but as club legend Joaquin Sanchez found the net to put his side 2-0 up against LaLiga champions Barcelona that's exactly what appeared to be on the cards.
We take a look ahead as Barcelona prepare to face Real Betis at the Camp Nou on Sunday.
Luis Enrique announced his Spain squad for their upcoming fixtures and recalled Jordi Alba to the squad. Despite this, there have been some high profile omissions including Marcos Alonso - '90min' selected their best XI who miss out.
Real Betis against AC Milan at the Villamarin always looked like being one of the most appealing games of this round of Europa League fixtures and Giovani Lo Celso ensured the Spaniards got off to the perfect start on home turf with a ruthless finish.
In a packed programme of early Europa League fixtures, Arsenal beat Sporting, Betis overcame Milan, Olympiakos triumphed against Dudelange, Leipzig downed Celtic and Salzburg saw off Rosenberg.
Real Betis continued their European adventure with an intimidating trip to San Siro to face fallen giants AC Milan on Thursday, with classy playmaker Giovani Lo Celso silencing the home crowd with a stunning second-half strike for the Andalusians.