Ukraine have made two changes from their opening game, with Anele Ngcongca and Roman Zozulyla being replaced by Serhiy Sydorchuk and Yevhen Seleznyov.
Northern Ireland have made five changes, which surprisingly sees their top scorer in qualifying Kyle Lafferty dropped to the bench.
Shane Ferguson, Conor McClaughlin, Chris Baird and Paddy McNair have all also been dropped. Aaron Hughes, Corry Evans, Stuart Dallas, Jamie Ward and Conor Washington enter the lineup.
Ukraine XI (4-5-1): Pyatov, Fedetskiy, Khacheridi, Rakitskiy, Shevchuk, Yarmolenko, Sydorchuk, Stepanenko, Konoplyanka, Kovalenko, Seleznyov.
Northern Ireland XI (4-3-3): McGovern, Hughes, Cathcart, McAuley, J Evans, Ward, C Evans, Davis, Norwood, Dallas, Washington.