The Chilean forward sparked outrage on social media after he posted a video launching a new clothing line.
In the video, Sanchez is seen posing with a model in a hotel room with several outfits to promote his 'JJO Alexis' brand.
However, given that his Man Utd side lost in such a disappointing manner to Brighton on Sunday, fans of the team were furious that the winger thought it was appropriate to post such a video.
Fans were not at all happy, replying to the tweet with comments such as "Not now Alexis!" and "Sanchez do you know we lost our match yesterday or were you busy with social media"
Sanchez himself was not involved in the game due to being injured, but quickly deleted the post because of the fans' reaction to it.