Wayne Rooney has made the 19-man squad to face Ukranian side Zorya Luhansk, after he missed the 1-1 draw with Everton through suspension. The United captain may get the opportunity to break another club record, as he finds himeslf just one goal behind Sir Bobby Charlton in the club's goalscoring charts in Europe.
Meanwhile, Eric Bailly is part of the squad that has travelled to Ukraine and may play for the first time since the 4-0 defeat to Chelsea after suffering a knee injury.
Michael Carrick has stayed at home due to suspension, while Chris Smalling and Luke Shaw remain injured.
Other absentees include Memphis Depay and Morgan Schneiderlin, who have not been considered for the game.
Manchester United will progress to the last-32 of the competition as long as they avoid defeat against the Ukranian side.