The two sides go into the game looking for wins for very different reasons, Leicester are hoping for their first away win under their French boss, whilst Newcastle will be looking to halt an alarming slide that has seen them undo a good start and slip down the Premier League table.
Speaking ahead of the game, Puel was asked about his attacking options and took the opportunity to laud England international Vardy.
"I think Jamie Vardy is the complete player. I would always prefer to have him in my team," Puel enthused.
"He's enjoying his football, it's amazing to see. He works hard for the team and always has a positive attitude.
"If we can help him to score it will be 50 goals, which is a good thing. He is a great player, and now with a lot of experience, maturity in the Premier League he can give a lot to the team. I was surprised to know his qualities.
"It's important to have different possibilities for players. Demarai Gray can play on the side, on the wing, behind Jamie and as a striker. He has all the quality.
"Shinji Okazaki works very hard for the team, and it is a pleasure to watch. Riyad Mahrez has the ability to play in this position too. He has a good understanding with Jamie. It's important to see in different games, different possibilities."