Potent new Juventus face Porto acid test

Juventus, beaten 3-1 by Barcelona in the 2015 final, are en route to a record sixth Serie A crown and remain many pundits' favourites to challenge the likes of Real Madrid for the trophy in Cardiff next May.

Massimiliano Allegri's Serie A league leaders head to Porto's Estadio do Dragao as favourites, but aware that they also ended Roma's hopes of even qualifying for the competition in clinical fashion last summer.

"Juventus are a top side who have made it to the final of the Champions League recently, so they will be a challenge for us," Porto president Pinto da Costa was quoted as saying in Corriere dello Sport.

"But Roma were also favourites against us, and in the end we won 3-0."

Allegri's decision to ditch his tried and trusted 3-5-2 for a more attack-minded 4-2-3-1 has seen Higuain, thanks to support from Juan Cuadrado, Paulo Dybala and Mario Mandzukic, pull level with Roma's Edin Dzeko at the top of the Serie A charts on 19 goals so far.

But while the Juventus front line is firing on all cylinders, Porto have reason to be targeting a makeshift Juve defence that could be missing key components in Andrea Barzagli and Giorgio Chiellini.

Both remain doubtful due to recent injury niggles, meaning either Daniele Rugani or Mehdi Benatia could partner Leonardo Bonucci in central defence.

Allegri's switch to a flat back four means Stephan Lichtsteiner, Dani Alves, Kwadwo Asamoah and Alex Sandro -- who are all adept as wingbacks in a five-man midfeld -- are all available for the left and right-back positions.

On Friday Allegri said: "Unless some strange things happen in the meantime, we will deploy a 4-2-3-1 in Portugal."

Both Rugani and Lichtsteiner were completely rested for Friday's 4-1 win over Palermo, in which Dybala hit a brace and Higuain hit one. Mario Mandzukic was also completely rested, suggesting he is a definite starter on Wednesday.

Allegri's two holding midfielders are likely to be Miralem Pjanic, the side's free-kick specialist, and Germany midfielder Sami Khedira. Italy international Claudio Marchisio, also on target against Palermo, is expected to start on the bench.

Porto might not be considered title winners, but Bonucci has done his homework.

"Maybe Porto aren't among the favourites for the quarter-finals, but we will be giving them maximum respect," the Italy defender told uefa.com.

"They went through a difficult period at the season but they've come bouncing right back in impressive fashion. They have some great young players and they'll will playing with the mentality that they nothing to lose.

"If we want to stay in Europe, we'll need a great performance on the night."

Porto have hit 14 league goals in their past five league games, all wins, and former Portugal defender Jorge Andrade, who played for both clubs, says scoring an away goal will be crucial for the Italians.

"The most important thing for Juventus will be to be vigilant in Oporto, and to score a goal," he told Tuttojuve.com.

"In Portugal people can't wait for this match. Don't forget that Porto have won the competition twice. Their key player will be (Tiquinho) Soares."

Soares has hit four goals in three games since joining Porto last month and will be looking to make his mark in a game featuring two legendary goalkeepers in Iker Casillas and Gianluigi Buffon.