The home team comes to the match after advancing in the Copa del Rey and in the seventh position of LaLiga after the defeat in the last game against Eibar in Ipurua by 2-0.
For their part, Barça are going through one of the best moments of the season after the good football shown in the recent away victories against SD Huesca (0-1) and Athletic Club (2-3). Against Granada, Ronald Koeman will be looking for a third straight win to keep them in the title race.
For the important clash, Diego Martinez will have to rest some after the cup match, especially with those players who come out of injury or face the commitment with certain inconveniences, such as Gonalons.
With Rui Silva fixed under sticks, the defense should be composed of Foulquier, Duarte, German and Neva. For his part, Gonalons, despite his problems, aims to start in the middle alongside Eteki and Herrera. Up front will be formed by Machís, Soldado and Luis Suárez.
Meanwhile, it is expected that Ronald Koeman will not make too many trials in a duel that seems more than evenly matched far from the Camp Nou and therefore he will line up a large part of the presumed gala team.
Ter Stegen will be the goalkeeper barring any shocks, while in the defence Mingueza aims to be the substitute of the sanctioned Lenglet. Together with him, Dest, Araujo and Jordi Alba will compose the azulgrana defence.
The double pivot will likely be formed by Frenkie de Jong and Sergio Busquets. In front of them would form the trio composed by Messi, Pedri and Dembélé. In front of all, in point, there could be Antoine Griezmann.
GRANADA: Rui Silva; Foulquier, Duarte, Germán, Neva; Gonalons, Herrera, Eteki; Luis Suárez, Soldado and Machís.
BARCELONA: Ter Stegen; Dest, Araujo, Mingueza, Jordi Alba; Busquets, De Jong; Messi, Pedri, Dembélé; and Griezmann.