Gundogan was substituted as a precaution in the Carabao Cup win over West Brom, while captain Kompany has been sidelined for four games since being injured on international duty.
City have enjoyed a blistering start to the new season, scoring 11 goals without response in the last two fixtures.
"The injury situation is OK," Guardiola said. "Vinny (Kompany) has come back. Gundogan we will see after training today (Friday).
"Last season we started quite well like this season, but last year we were not good enough to fight against the best teams. But it is important that we are there; my only regret last season is that we were not able to fight until the end.
"I think I am a good manager. We are humble and we fight like a normal team. I believe in the quality of the way we play.
"This is the Premier league. I hear from the beginning every single team can beat the other one."
Guardiola’s side may sit at the top of the Premier League table, but the Spanish tactician is not taking the Palace test lightly.
"I have a lot of respect for what I saw from Palace against Southampton and Burnley," Guardiola added. "They created a lot of chances. I showed to my players all the chances they created in just two games.
"They will put a lot of long balls into the box and crosses but I admire Roy Hodgson, he has had a long career and that always deserves respect."