James makes Manchester United's starting XI for West Ham encounter
Ole Gunnar Solskjaer included the in-form winger in his starting XI for Sunday's meeting at the London Stadium despite him suffering a knock during last weekend's 1-0 victory over Leicester City.
The 21-year-old's availability means United go in with the same team that saw off the Foxes courtesy of Marcus Rashford's early penalty.
James skipped the midweek Europa League win over Astana and will have an important part to play against the Hammers as manager Solskjaer seeks a more ruthless showing from the goal-shy Red Devils.
Mason Greenwood, scorer of the only goal against Astana, does not make the matchday 18 due to illness, while stars Paul Pogba and Anthony Martial remain unavailable.
West Ham are without injured midfielder Manuel Lanzini, with Pablo Fornals his replacement.