In the last three times he has played at Santiago Bernabeu Antoine Griezmann has scored, meaning that he likes the occasion of playing Atletico's more successful city rivals.
In the 26 games that the French forward has played, he has scored on seven occasions. His most memorable goal for the 'red and whites' in the fixture has to be in the 4-0 defeat of their rivals that helped sink Carlo Ancelotti's reign.
After three goals in the league and one in the Champions League since then, it seems as though the World Cup winner could pose the most significant attacking threat to the Real Madrid goal.
The European champions, and particularly the trio of Bale, Benzema and Asensio, have faltered in the last two league games after only scoring two in their last three games.
It therefore seems that Griezmann is the more likely to win in the battle of the attacks, but we'll only know for sure when the whistle blows on Saturday.