Egypt: It seems talisman Mohamed Salah has beaten his fitness concerns over a shoulder injury and looks a likely contender to play some part in his side's group stage opener. Should Salah not start, however, expect Ramadan Sobhi to be his immediate replacement on the wing.
Goalkeeper Essam El-Hadary is the oldest player at this summer's tournament at 45 years old, and could even captain Egypt for the first time at a World Cup.
Uruguay: Luis Suarez and Edinson Cavani will undoubtedly be the South American side's two most potent attacking threats and will be vying for the tournament's Golden Boot.
In other areas, Arsenal target Lucas Torreira and former Barcelona left-back Martin Carceres are both in contention for starts against Egypt.
Egypt coach Hector Cuper on not relying on Salah:
“We’re not Mohamed Salah’s national team, this team has many players who cooperate with each other to reach the best results. The most important thing is that the team finds a good balance in its performance.
“Egypt is lucky that this generation has one of the best players in the world but our tactics don’t solely revolve around him.
Uruguay coach Oscar Tabarez on Luis Suarez's discipline:
"Luis Suarez is no doubt more mature now and he has matured a great deal. What happened in Brazil is part of real life and of course a lesson to achieve more maturity not only as a footballer but also in other parts of his life, such as his family.
"He's got the right mindset for this World Cup and he is meeting all my expectations. In addition to being a great player, he is very smart, very intelligent and we are going to really capitalise on him".
Did you know?
The two sides have only ever played each other once, with Uruguay coming out on top 2-0 during an international friendly in 2006.
Prediction: 0-2
Possible lineups:
Egypt: El-Hadary, Fathi, Hegazi, Gabr, Shafy, Hamed, Elneny, Trezeguet, Said, Salah.
Uruguay: Muslera; Caceres, Gimenez, Godin, Pereira; Bentancur, Torreira; Rodriguez, Arrascaeta, Suarez; Cavani.