Barcelona visit Rayo Vallecano in a La Liga tricky match at the Vallecas stadium, which kicks off at 14:00 CET.
The 'Cules' are third on thirty points, two behind arch-rivals Real Madrid and four behind La Liga leaders Girona, so a slip-up against Francisco's side would be a fatal blow to their bid for the domestic championship title.
For their part, the Madrid side got off to a flying start to the season but have slumped in their last few games, so Rayo Vallecano will be looking to get back to winning ways and claim a shock victory over Xavi Hernandez's side.
CONFIRMED lineups for the clash
Barcelona starting XI: Pena; Joao Cancelo, Christensen, Inigo Martinez, Balde; De Jong, Oriol Romeu, Pedri; Lamine Yamal, Lewandowski and Ferran Torres
Rayo Vallecano starting XI: Dimitrievski; Ivan Balliu, Mumin, Lejeune, Pacha Espino; Unai Lopez, Oscar Valentin; Isi Palazon, Trejo, De Frutos; and Camello.