Brighton: Star midfielder Pascal Gross is the only absentee for the 'seagulls'. Jose Izquierdo and Florin Andone coulod make their first appearances of the season after returning to fitness.
Tottenham: Dele Alli and Moussa Sissoko could feature after both returning to training from hamstring injuries, but Pochettino will not rush them back. Hugo Lloris remains out with a thigh issue, Kieran Trippier and Toby Alderweireld could return after being rested against Inter.
Brighton boss Chris Hughton: "[Tottenham] are a team that don't lose many games and by their standards are having a difficult time.
"And that's the time perhaps when they are at their most dangerous.
"They've got great, great quality. We know that we'll have to play at a really good level to get something from the game."
Tottenham boss Mauricio Pochettino: ''The group is ok. The group is of course a little bit anxious about winning games because it's normal when you don't win.
"Sometimes it's good to feel the pain, the defeat, not only the one, two but three. It's so important to be clever and be strong. Football is like life, it's impossible to keep 70 years of happiness.
"There is always a period of ups and downs and football is the same, ups and downs, and it's so important to learn from that period and keep calm."
Form:
Did You Know?
This is Tottenham's longest run of consecutive defeats (three) since Maurico Pochettino was appointed manager in 2014
Brighton manager Chris Hughton played for Tottenham from 1977 to 1990, making 297 appearances and worked at the club as an coach and assistant manager from 1993 to 2007
Brighton predicted lineup: Ryan; Montoya, Duffy, Dunk, Bong; Knockart, Stephens, Propper, Bissouma, March, Murray
Tottenham predicted lineup: Vorm; Trippier, Alderweireld, Vertonghen, Rose, Wanyama, Winks, Moura, Eriksen, Son, Kane
Prediction: 1-2