Phil Foden - Man City (28/05/2000)
Foden became the youngest ever player to receive a Premier League winner's medal at the end of 2017/18, after playing five times during City's march to the title. The England U19 World Cup winner made his Premier League debut in a 4-1 victory against Tottenham Hotspur.
Ryan Sessegnon - Fulham (18/05/2000)
Ryan Sessegnon made his debut against Crystal Palace at the start of the 2018-19 season.
Morgan Gibbs-White - Wolves (21/01/2000)
The Wolves academy graduate made his debut in the Premier League against Southampton and went on to star in a 1-1 draw at Old Trafford the week later.
Callum Hudson-Odoi - Chelsea (07/11/2000)
Hudson-Odoi made his Premier League debut coming on as a substitute on 31 January in a 3–0 home loss to Bournemouth.
Ethan Ampadu - Chelsea (14/09/2000)
Ampadu replaced Andreas Christensen on 79 minutes as Chelsea beat Huddersfield Town 3-1 to make his Premier League debut for the club. He has also made his full international debut for Wales.
Angel Gomes - Manchester United (31/08/2000)
Angel Gomes became the first player born this century to play in the Premier League. Angel Gomes came on as an 88th-minute substitute for Manchester United against Crystal Palace - at the age of 16 years and 263 days old.
Michael Obafemi - Southampton (06/07/2000)
Obafemi made his professional debut as a substitute in the 82nd minute of a 1–1 draw with Tottenham Hotspur on 21 January 2018.
Rekeem Harper - West Bromwich Albion (08/03/2000)
Harper made his professional Albion debut on 12 August 2017 as a second-half substitute in the West Brom's 1–0 win over Bournemouth, in doing so becoming only the second Premier League player to have been born in the 2000s