Claudio Ranieri has again refused to make any changed from his preferred starting XI. Leonardo Ulloa and Shinji Okazaki pair up again up front in the absence of the suspended Jamie Vardy, while PFA Player of the Year Riyad Mahrez plays behind them.
Louis van Gaal makes just one change from the side that beat Everton in the FA Cup semi-final, with Antonio Valencia replacing Timothy Fosu-Mensah.
Club captain Wayne Rooney again starts in the deeper midfield role, whilst youngster Marcus Rashford leads the atttack.
Man Utd XI (4-5-1): De Gea, Valencia, Smalling, Blind, Rojo, Carrick, Fellaini, Lingard, Rooney, Martial, Rashford.
Subs: Depay, Mata, Romero, Ander Herrera, Schneiderlin, Darmian, Fosu-Mensah.
Leicester XI (4-4-2): Schmeichel, Simpson, Morgan, Huth, Fuchs, Mahrez, Kante, Drinkwater, Schlupp, Okazaki, Ulloa.
Subs: King, Albrighton, Amartey, Gray, Wasilewski, Chilwell, Schwarzer.