Manchester United:
Jose Mourinho has no fresh injury concerns on a day where his side could clinch qualification for the last 16. They will progress from Group A if they win and CSKA Moscow fail to beat Basel, or if United draw and CSKA lose.
Long-term absentees Michael Carrick, Marouane Fellaini, Paul Pogba, Zlatan Ibrahimovic and Marcos Rojo all remain sidelined, but Eric Bailly and Phil Jones should be fit enough to play.
Befnfica:
The visitors, who have never kept a clean sheet against the Red Devils (10 games), will be without Jardel due to injury, while Luisao and Andre Almeida are ruled out because of suspension.
Recent form:
Possible lineups:
Manchester United: De Gea; Bailly, Jones, Smalling; Valencia, Herrera, Matic, Young; Mkhitaryan, Martial; Lukaku.
Befnfica: Svilar; Douglas, Dias, Eliseu, Grimaldo; Fejsa, Pizzi, Augusto, Goncalves, Salvio; Seferovic.