The former Malaga midfielder has found himself way down the pecking order at the Bernabeu, but according to the 'Mirror', Spurs are preparing an offer for the Spaniard.
Isco swapped the Costa del Sol for the Spanish capital in 2013 and has since made 151 appearances for Real Madrid, scoring 22 goals.
The 24-year-old has also won two Champions League trophies with Madrid amongst other trophies.
The midfielder also has 14 caps for Spain, scoring one international goal.
Would the Spaniard be a good signing for Tottenham?