Isco hasn't been part of the starting team since the 9th of August. He played in the Super Cup against Sevilla the last time from the beginning. Since then, he wasn't part of the starting team.
The number of minutes he played is little. Concerning his playing time, he's Madrid's number 20 in the ranking.
Even if he wasn't available during some games due to injuries, he could have played in seven games and in three of them he didn't even went onto the pitch (Sporting, Villarreal and Borussia Dortmund).
A weird situation for Isco, who was one of Zidane favourite players. But it seems like the Frenchman doesn't count this season that much on the youngster.